Growth Hormone Replacement

WHAT IS SERMORELIN?

Sermorelin Acetate is one of several “HGH Secretagoues.” A Secretagoue is a hormone or agent that stimulates the increased production of another hormone. In the case of Sermorelin, stimulating the increased production of Human Growth Hormone (HGH). Sermorelin works by naturally stimulating our body to increase its production of Human Growth Hormone.

What are Growth Hormone Releasing Peptides?

In many cases Sermorelin Therapy will also include the use of a Growth Hormone Releasing Peptide (GHRP). Growth Hormone Releasing Peptides are another class of very effective HGH Secretagoues, GHRP-6 and GHRP-2 being two of the most potent. Incorporating these GHRPs with the use of Sermorelin makes for a very powerful and effective treatment, fully maximizing the production of HGH by the body.

AT PRIMEAESTHETICA WE USE A COMBINATIONOF ALL THREE PRODUCTS TO ACHIEVE THE MAXIMUM DESIRED RESPONSE

There are many advantages of using sermorelin for hGH replacement therapy rather than hGH itself, both in terms of safety as well as accessibility and cost.

SAFETY: Administration of hGH is associated with a range of adverse side-effects. These include, but are not limited to, bone  growth abnormalities, diabetes and heart disease .  

Sermorelin on the other hand, has not been associated with the same side-effects as hGH.

Sermorelin does not shut down the body’s own production of hGH but instead supports pituitary function and promotes natural production of hGH.

ACCESSIBILITY: Then there are the safety concerns surrounding use of hGH which arise from its status as a ‘controlled substance’. Legally doctors can only prescribe hGH for children with human growth hormone deficiency.

Sermorelin, in comparison, is not governed by the same strict laws of medical use and this is largely due to its safety profile. For this reason, sermorelin is much more accessible and is commonly prescribed by doctors in anti-aging and wellness clinics in conjunction with other growth hormone releasing peptides such as GHRP-2 and GHRP-6.

COST: hGH typically costs >$1000 per month of treatment. Sermorelin is a much more affordable option with 3 months treatment costing less than just one month on hGH.

Perhaps the easiest way to understand the potential benefits of hGh replacement therapy is to look at the symptoms of hGH decline and the effect hGH replacement has on those symptoms. These are detailed below:

1. Changes in Body Composition

Changes in body composition due to decreasing levels of hGH are reflected by a decrease in lean body mass (muscle) and an increase in fat mass. Correcting hGH levels has been shown to reverse this state by improving muscle mass and reducing fat.

2. Bone Mineral Density

Research indicates that hGH deficiency in adults contributes to a reduction in bone density and therefore increased risk of osteoporosis. It has also been shown that hGH replacement therapy for greater than 12 months results in improved bone mineral density and hence, lower risk of osteoporosis.

3. Muscle Strength

Due to changes in body composition detailed above, muscle strength is understandably compromised. As hGH therapy corrects body composition and improves muscle mass, muscle strength also improves. The best results are gained after 12 months of hGH therapy.

4. Exercise Performance

Exercise performance is reduced in individuals with growth hormone deficiency. This appears to be partially due to reductions in bone density and muscle mass but also in part due to a reduction in oxygen uptake. hGH therapy for 6 months has been shown to improve exercise performance by improving muscle mass and also oxygen uptake

5. Heart Health

There is evidence of a greater risk of heart disease in individuals with growth hormone deficiency and it has been hypothesized that this is due to a greater propensity to develop premature atherosclerosis (a build-up of plaque inside the arteries which increases risk of heart attack and stroke). Growth hormone deficiency also results in changes in heart size and function. These changes have been demonstrated to be reversed after 6 months hGH therapy.

6. Metabolism

Growth hormone deficiency results in a reduced resting metabolism and replacement therapy reverses this decrease. hGH therapy has also been shown to increase protein synthesis, increase fat oxidation, normalize carbohydrate metabolism and reduce LDL (bad) cholesterol. These favorable effects on metabolism may in part explain some of the other benefits of hGH including improved hearth health and body composition.

7. Skin Thickness

A reduction in skin thickness and all-important skin collagen is another result of growth hormone deficiency. Both conditions are improved by hGH therapy.

8. Immune Function

Although adults with growth hormone deficiency are not normally considered to have a compromised immune system, there is some evidence to suggest that hGH therapy can help regulate immune function.

9. Libido

It has been demonstrated that people with growth hormone deficiency have more difficulty with sexual relationships and reportedly, lower energy levels. Many individuals have found an improvement in energy, libido and sexual performance following hGH therapy, some men even claiming an improvement in problems with premature ejaculation.

10. Quality of Life

Reduced psychological well-being has been reported in individuals with growth hormone deficiency and hGH replacement has resulted in improvements in mood, energy and general feelings of well-being.

Related Blog Post: Sermorelin Injections for Improved Health